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maandag 30 januari 2012

Factors that may possibly induce liver disease

Host factors that may enhance susceptibility to drugs, possibly inducing liver disease


Female - Halothane, nitrofurantoin, sulindac

Male - Amoxicillin-clavulanic acid (Augmentin)

Old age - Acetaminophen, halothane, INH, amoxicillin-clavulanic acid

Young age - Salicylates, valproic acid

Fasting or malnutrition - Acetaminophen

Large body mass index/obesity - Halothane

Diabetes mellitus - Methotrexate, niacin

Renal failure - Tetracycline, allopurinol

AIDS - Dapsone, trimethoprim-sulfamethoxazole

Hepatitis C - Ibuprofen, ritonavir, flutamide

Preexisting liver disease - Niacin, tetracycline, methotrexate


Source: http://emedicine.medscape.com/article/169814-overview

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