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zaterdag 7 januari 2012

Kayser-Fleischer Ring or mononucleosis?

Kayser-Fleischer Ring

The ring encircling the iris of the eye is known as ‘Kayser-Fleischer ring’. These are dark rings which are the result of copper deposition. This copper deposition occurs in patients suffering from liver related diseases. Found in descemet’s membrane and can extend into tabecular meshwork. It first appears as a crescent at top of the cornea.

This ring for identification requires a slit-lamp examination in its early stage. These rings are considered as a sign of Wilson’s disease and may be a result of abnormalities in basal ganglia of the brain, liver cirrhosis, muscle rigidity and involuntary movements. Copper chelation can be used as a therapy.


When hepatitis develops, patients are often thought to have infectious hepatitis or infectious mononucleosis when they actually have Wilson disease hepatitis.