Vandaag is verwendag. Een bon bij een beauty-instituut. Het ligt hier al bijna een jaar. Al die tijd uitgesteld omdat het veelal onmogelijk was om twee uur non-stop uit huis te zijn, de verplaatsingen niet meegerekend. Mijn uitspattingen (lees moederlijke taken) concentreer ik meestal op een zaterdag en betaal dan het gelag de rest van de week.
Hubby heeft een dagje vrij en brengt me alvast. Anderhalf uur lang smeert en wrijft een lieve jongedame mijn droog vel soepel. Mijn voeten worden gemasseerd en voelen vederlicht aan. Ik blink en geur als een bloemetje bij het buitenkomen.
maandag 28 februari 2011
Dag 379 Slapeloos
De jongste voelt zich weer slechter de laatste dagen. Hoofdpijn, buikpijn, keelpijn, ... en slapen is nog steeds een ramp.
Ook al erger ik me blauw aan het feit dat een kind meerder malen aan mijn bed staat met de melding dat ie niet kan slapen, diep vanbinnen besef ik dat het wel eens een probleem van ME/cvs zou kunnen zijn. Onze hersenen zijn ook verstoord om degelijk te kunnen slapen.
Deze ochtend stond de ronde vlek weer op zijn kaak, net zoals ik ze heb. Hij wil niet naar school. Ik neem een foto voor de kinderarts of wie het ooit wil aanvaarden als “aanwijzing”. Hij blijft in zijn bedje liggen, springt er niet uit als anders en ik laat hem liggen. Hij slaapt al zo weinig.
Als ik hem niet au serieux neem, wie zal het dan ooit doen?
Ook al erger ik me blauw aan het feit dat een kind meerder malen aan mijn bed staat met de melding dat ie niet kan slapen, diep vanbinnen besef ik dat het wel eens een probleem van ME/cvs zou kunnen zijn. Onze hersenen zijn ook verstoord om degelijk te kunnen slapen.
Deze ochtend stond de ronde vlek weer op zijn kaak, net zoals ik ze heb. Hij wil niet naar school. Ik neem een foto voor de kinderarts of wie het ooit wil aanvaarden als “aanwijzing”. Hij blijft in zijn bedje liggen, springt er niet uit als anders en ik laat hem liggen. Hij slaapt al zo weinig.
Als ik hem niet au serieux neem, wie zal het dan ooit doen?
Dag 378 Neus
De effecten van de verhoging van de LDN manifesteren zich. Het gezeur en ziekelijke gevoel in de borstkast is terug. Alsof er een vuurtje in brandt. In tegenstelling tot gisteren weinig fit vandaag. Het lichaam reageert instant op de substantie. Mijn bewustzijn verandert licht als ik het inneem vlak voor het slapengaan.
De griep is nu 3 weken geleden begonnen. Wat rest is een knallende hoofdpijn bij elke hoestbui of bukken. Alsof mijn aders springen in mijn hoofd. Nog even en het is voorbij.
De AB deed de loopneus gedurende een vijftal dagen stoppen maar nu zijn het weer dikke gekleurde slijmen. Er is straffer spul voor nodig. De zakdoekenindustrie verdient goed aan mij.
De griep is nu 3 weken geleden begonnen. Wat rest is een knallende hoofdpijn bij elke hoestbui of bukken. Alsof mijn aders springen in mijn hoofd. Nog even en het is voorbij.
De AB deed de loopneus gedurende een vijftal dagen stoppen maar nu zijn het weer dikke gekleurde slijmen. Er is straffer spul voor nodig. De zakdoekenindustrie verdient goed aan mij.
zondag 27 februari 2011
vrijdag 25 februari 2011
Getuigenissen kinderen met ME/CVS, fibromyalgie, e.a.
I.v.m. met de protestactie op 14 maart neemt Nancy DD de getuigenissen van kinderen voor haar rekening. Ze vat deze samen en deze zullen overhandigd worden aan de minister van gezondheid.
Schrijf haar via mail jullie getuigenissen, ondervindingen, enz. want het betreft hier de zwaksten onder ons. Ook zou ze graag van jullie (en mensen rondom jullie) de namen en leeftijden van kinderen die ME/CVS, fibromyalgie e.d. hebben, ontvangen zodat ze samen met het logo dat ze eerder voorstelde, een groot doek kan maken of aparte affiches.
Er rest ons maar 2 weekjes om dit rond te krijgen .... dus snel reageren ajb! Dank je wel alvast!
Druk even op de reageer knop onderaan en je krijgt per kerende het email adres van Nancy.
Schrijf haar via mail jullie getuigenissen, ondervindingen, enz. want het betreft hier de zwaksten onder ons. Ook zou ze graag van jullie (en mensen rondom jullie) de namen en leeftijden van kinderen die ME/CVS, fibromyalgie e.d. hebben, ontvangen zodat ze samen met het logo dat ze eerder voorstelde, een groot doek kan maken of aparte affiches.
Er rest ons maar 2 weekjes om dit rond te krijgen .... dus snel reageren ajb! Dank je wel alvast!
Druk even op de reageer knop onderaan en je krijgt per kerende het email adres van Nancy.
donderdag 24 februari 2011
The Promise of the Proteome
In an article titled, "Distinct Cerebrospinal Fluid Proteomes Differentiate Post-Treatment Lyme Disease and CFS," Steven Schutzer and colleagues from six institutions tested samples collected by lumbar puncture from 43 CFS subjects, 25 subjects with documented Lyme disease who did not recover after standard antibiotic treatment (referred to in this paper as "nPTLS") and 11 healthy controls.
Using mass spectroscopy and liquid chromatography, the team was able to generate a comprehensive list of 30,000 peptides in the cerebrospinal fluid (CSF) samples pooled from subjects in each disease group. Of these 30,000 peptides, 738 proteins were found only in CFS subjects. The nPTLS samples had 692 unique proteins and the normal controls had 724 unique proteins. Differences in the amounts of various proteins were detected between groups and CFS and nPTLS had more proteins in common than with the healthy controls.
Looking at the biological pathways implicated by the different proteins identified, the team found that proteins in the complement cascade were elevated in abundance in the pooled nPTLS and CFS samples compared to controls, but at different levels for the two disease groups. The complement system is a part of the immune system that helps to clear infectious pathogens. Proteins involved in the CDK5 signaling pathway were significantly enriched in the CFS samples. Alterations in the CDK5 signaling pathway have been linked to Parkinson's disease and Alzheimer's disease.
By analyzing individual CSF samples, they determined that nPTLS patients are distinct from CFS patients. The ability to distinguish CFS and nPTLS on the basis of these proteins has important diagnostic implications. It also suggests different treatment approaches may be warranted. Some have proposed that nPTLS represents a subset of CFS; however, the authors of this paper conclude that their data does not support that concept.
In the final discussion section, the authors state, "CSF proteome analysis may provide important and meaningful insights into the biological processes modulated as a function of disease and facilitate the identification of protein candidates for further investigation." They suggest that by uncovering these candidates in cerebrospinal fluid, a targeted search in blood for these proteins is now possible.
This team of researchers provided the comprehensive list of proteins they identified as part of the open access paper. This will enable these and other investigators to explore and interrogate the data further. The collaborative effort across six institutions and multiple funding partners, use of new technologies for discovery and willingness to openly share data to advance the field represent an inspiring 21st century research initiative worthy of high hopes.
Schutzer SE, Angel TE, Liu T, Schepmoes AA, Clauss TR, Adkins NJ, Camp DG, Holland BK, Bergquist J, Coyle PK, Smith RD, Fallon BA, Natelson BH. (2011) Distinct cerebrospinal fluid proteomes differentiate post-treatment Lyme disease from chronic fatigue syndrome. PLoS ONE 6(2): e17287. doi:10.1371/journal.pone.0017287
Click here to read the unabridged version of "The Promise of the Proteome"
Using mass spectroscopy and liquid chromatography, the team was able to generate a comprehensive list of 30,000 peptides in the cerebrospinal fluid (CSF) samples pooled from subjects in each disease group. Of these 30,000 peptides, 738 proteins were found only in CFS subjects. The nPTLS samples had 692 unique proteins and the normal controls had 724 unique proteins. Differences in the amounts of various proteins were detected between groups and CFS and nPTLS had more proteins in common than with the healthy controls.
Looking at the biological pathways implicated by the different proteins identified, the team found that proteins in the complement cascade were elevated in abundance in the pooled nPTLS and CFS samples compared to controls, but at different levels for the two disease groups. The complement system is a part of the immune system that helps to clear infectious pathogens. Proteins involved in the CDK5 signaling pathway were significantly enriched in the CFS samples. Alterations in the CDK5 signaling pathway have been linked to Parkinson's disease and Alzheimer's disease.
By analyzing individual CSF samples, they determined that nPTLS patients are distinct from CFS patients. The ability to distinguish CFS and nPTLS on the basis of these proteins has important diagnostic implications. It also suggests different treatment approaches may be warranted. Some have proposed that nPTLS represents a subset of CFS; however, the authors of this paper conclude that their data does not support that concept.
In the final discussion section, the authors state, "CSF proteome analysis may provide important and meaningful insights into the biological processes modulated as a function of disease and facilitate the identification of protein candidates for further investigation." They suggest that by uncovering these candidates in cerebrospinal fluid, a targeted search in blood for these proteins is now possible.
This team of researchers provided the comprehensive list of proteins they identified as part of the open access paper. This will enable these and other investigators to explore and interrogate the data further. The collaborative effort across six institutions and multiple funding partners, use of new technologies for discovery and willingness to openly share data to advance the field represent an inspiring 21st century research initiative worthy of high hopes.
Schutzer SE, Angel TE, Liu T, Schepmoes AA, Clauss TR, Adkins NJ, Camp DG, Holland BK, Bergquist J, Coyle PK, Smith RD, Fallon BA, Natelson BH. (2011) Distinct cerebrospinal fluid proteomes differentiate post-treatment Lyme disease from chronic fatigue syndrome. PLoS ONE 6(2): e17287. doi:10.1371/journal.pone.0017287
Click here to read the unabridged version of "The Promise of the Proteome"
Lavendelolie blijkt sterke anti-schimmel eigenschappen te hebben
Lavender oil has potent antifungal effect
Lavender oil could be used to combat the increasing incidence of antifungal-resistant infections, according to a study published in the Journal of Medical Microbiology. The essential oil shows a potent antifungal effect against strains of fungi responsible for common skin and nail infections.
Scientists from the University of Coimbra in Portugal distilled lavender oil from the Lavandula viridis L'Hér shrub that grows in southern Portugal. The oil was tested against a range of pathogenic fungi and was found to be lethal to a range of skin-pathogenic strains, known as dermatophytes, as well as various species of Candida.
Dermatophytes cause infections of the skin, hair and nails as they use the keratin within these tissues to obtain nutrients. They are responsible for conditions such as Athletes' foot, ringworm and can also lead to scalp and nail infections. Candida species coexist with most healthy individuals without causing problems but may cause mucocutaneous candidosis - or thrush - in some people. In immunocompromised patients, Candida species are able to cause serious infection if the fungal cells escape into the blood stream.
Currently, there are relatively few types of antifungal drugs to treat infections and those that are available often have side effects. Professor Lígia Salgueiro and Professor Eugénia Pinto who led this study explained why novel fungicides are urgently needed. "In the last few years there has been an increase in the incidence of fungal diseases, particularly among immunocompromised patients," they said. "Unfortunately there is also increasing resistance to antifungal drugs. Research by our group and others has shown that essential oils may be cheap, efficient alternatives that have minimal side effects."
Essential oils distilled from the Lavandula genus of lavender plants are already used widely, particularly in the food, perfume and cosmetic industries. Studies of the biological activities of these oils suggest Lavandula oils have sedative and antispasmodic properties as well being potent antimicrobials and antioxidants.
This group has demonstrated that these oils work by destroying fungal cells by damaging the cell membrane. They believe that further research into the mechanisms by which this essential oil works could have significant clinical benefits. "Lavandula oil shows wide-spectrum antifungal activity and is highly potent. This is a good starting point for developing this oil for clinical use to manage fungal infections. What is now required is clinical trials to evaluate how our in vitro work translates in vivo," said Professor Salgueiro.
Lavender oil could be used to combat the increasing incidence of antifungal-resistant infections, according to a study published in the Journal of Medical Microbiology. The essential oil shows a potent antifungal effect against strains of fungi responsible for common skin and nail infections.
Scientists from the University of Coimbra in Portugal distilled lavender oil from the Lavandula viridis L'Hér shrub that grows in southern Portugal. The oil was tested against a range of pathogenic fungi and was found to be lethal to a range of skin-pathogenic strains, known as dermatophytes, as well as various species of Candida.
Dermatophytes cause infections of the skin, hair and nails as they use the keratin within these tissues to obtain nutrients. They are responsible for conditions such as Athletes' foot, ringworm and can also lead to scalp and nail infections. Candida species coexist with most healthy individuals without causing problems but may cause mucocutaneous candidosis - or thrush - in some people. In immunocompromised patients, Candida species are able to cause serious infection if the fungal cells escape into the blood stream.
Currently, there are relatively few types of antifungal drugs to treat infections and those that are available often have side effects. Professor Lígia Salgueiro and Professor Eugénia Pinto who led this study explained why novel fungicides are urgently needed. "In the last few years there has been an increase in the incidence of fungal diseases, particularly among immunocompromised patients," they said. "Unfortunately there is also increasing resistance to antifungal drugs. Research by our group and others has shown that essential oils may be cheap, efficient alternatives that have minimal side effects."
Essential oils distilled from the Lavandula genus of lavender plants are already used widely, particularly in the food, perfume and cosmetic industries. Studies of the biological activities of these oils suggest Lavandula oils have sedative and antispasmodic properties as well being potent antimicrobials and antioxidants.
This group has demonstrated that these oils work by destroying fungal cells by damaging the cell membrane. They believe that further research into the mechanisms by which this essential oil works could have significant clinical benefits. "Lavandula oil shows wide-spectrum antifungal activity and is highly potent. This is a good starting point for developing this oil for clinical use to manage fungal infections. What is now required is clinical trials to evaluate how our in vitro work translates in vivo," said Professor Salgueiro.
zondag 20 februari 2011
Een psychiatrische diagnose kan men niet bewijzen
Psychiatric diagnoses prone to abuse
Note from CCHR: The below article is short but the point made by author Richard Vatz, Professor of political rhetoric, is all to often overlooked—quite simply that psychiatric diagnoses are completely subjective and there is no known scientific or medical means by which any “psychiatric diagnosis” can be proven. For more information see video of CCHR Co-founder, Professor Thomas Szasz, Professor of Psychiatry Emeritus, of whom Vatz has called, “the preeminent critic of psychiatry in the world.” http://www.cchrint.org/videos/experts/thomas-szasz/
The Baltimore Sun, November 8, 2010
by Richard E. Vatz, Professor of political rhetoric at Towson University.
One of the few issues not thoroughly covered in Scott Calvert’s well-researched, comprehensive articles on Baltimore Behavioral Health (“Hooked on treatment,” Nov. 7 and “Sheltered addicts, strained recovery,” Nov. 8) is why psychiatric diagnoses are particularly prone to misdiagnosis and overdiagnosis.
The reason is that psychiatric diagnosis is not based on pathological criteria. The closest the article comes to addressing this problem is the statement that “Even in the best clinical scenario, a psychiatric diagnosis is tricky, experts say; doctors have no X-rays to help apply the criteria defining a mental illness.”
In fact a diagnosis can never be indisputably ruled in or ruled out in psychiatry. All we have is testimony by differing psychiatrists, psychologists and social workers. In somatic medicine there is an array of pathological tests which often permit much greater diagnostic certainty. A biopsy of a lump in the breast will almost always tell you whether it’s benign or malignant.
The ability of professionals and patients to play the system financially and to exculpate addicts from responsibility will forever be aided by makeshift diagnoses which can neither be confirmed nor ruled out.
Richard E. Vatz
http://articles.baltimoresun.com/2010-11-08/news/bs-ed-pschiatric-diagnoses-letter-20101108_1_psychiatric-diagnoses-criteria-addicts
For more information on psychiatry as a pseudo-science, visit CCHR’s Thomas Szasz pages http://www.cchrint.org/about-us/co-founder-dr-thomas-szasz/
Mijnheer Van Houdenhove & Co, uw zogezegde evidence based medicine bestaat niet. Onze medische afwijkingen wél.
Note from CCHR: The below article is short but the point made by author Richard Vatz, Professor of political rhetoric, is all to often overlooked—quite simply that psychiatric diagnoses are completely subjective and there is no known scientific or medical means by which any “psychiatric diagnosis” can be proven. For more information see video of CCHR Co-founder, Professor Thomas Szasz, Professor of Psychiatry Emeritus, of whom Vatz has called, “the preeminent critic of psychiatry in the world.” http://www.cchrint.org/videos/experts/thomas-szasz/
The Baltimore Sun, November 8, 2010
by Richard E. Vatz, Professor of political rhetoric at Towson University.
One of the few issues not thoroughly covered in Scott Calvert’s well-researched, comprehensive articles on Baltimore Behavioral Health (“Hooked on treatment,” Nov. 7 and “Sheltered addicts, strained recovery,” Nov. 8) is why psychiatric diagnoses are particularly prone to misdiagnosis and overdiagnosis.
The reason is that psychiatric diagnosis is not based on pathological criteria. The closest the article comes to addressing this problem is the statement that “Even in the best clinical scenario, a psychiatric diagnosis is tricky, experts say; doctors have no X-rays to help apply the criteria defining a mental illness.”
In fact a diagnosis can never be indisputably ruled in or ruled out in psychiatry. All we have is testimony by differing psychiatrists, psychologists and social workers. In somatic medicine there is an array of pathological tests which often permit much greater diagnostic certainty. A biopsy of a lump in the breast will almost always tell you whether it’s benign or malignant.
The ability of professionals and patients to play the system financially and to exculpate addicts from responsibility will forever be aided by makeshift diagnoses which can neither be confirmed nor ruled out.
Richard E. Vatz
http://articles.baltimoresun.com/2010-11-08/news/bs-ed-pschiatric-diagnoses-letter-20101108_1_psychiatric-diagnoses-criteria-addicts
For more information on psychiatry as a pseudo-science, visit CCHR’s Thomas Szasz pages http://www.cchrint.org/about-us/co-founder-dr-thomas-szasz/
Mijnheer Van Houdenhove & Co, uw zogezegde evidence based medicine bestaat niet. Onze medische afwijkingen wél.
Wanneer een psychiater het kamp van patienten kiest
Psychiatrists had to invent their own book of diseases because pathologists would have nothing to do with them. It is called the Diagnostic and Statistic Manual for Mental Disorders, the DSM.
A great work of ... fiction.
vrijdag 18 februari 2011
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